منابع مشابه
Colorful molecular diagnostics.
Most diagnostic assays used daily in clinical laboratories are based on identifying and quantifying the presence of specific molecules that serve as markers of pathologic conditions and physiological status; however, these molecules are neither visualized nor counted directly. Instead, amplified signals generated through various strategies [e.g., real-time PCR, enzyme-linked assays (ELISAs), or...
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Introduction: Genetics, cellular and molecular medicines are cutting-edge sciences and technologies that play an important role in improving human health and quality of life. In addition, medical and biological sciences have clearly shown that the onset of diseases differs from person to person due to their different genetic profiles and variations in molecular basis. Therefore, it is feasible ...
متن کاملMolecular beacons: colorful analysis of nucleic acids.
The completion of the Humane Genome Project has resulted in an exponential rise in the demand for molecular diagnostic assays. To meet this demand, several innovative technologies have become available for performing homogeneous genetic analyses. For this type of assay, special detector probes are necessary. In 1996, Tyagi and Kramer described fluorogenic hairpin-shaped detector probes, called ...
متن کاملMolecular Diagnostics
The laboratory medicine is advancing towards the use of molecular techniques and molecular diagnostics for the detection of leukemia, genetic disorders, preimplantation screenings, pharmacogenomics, infectious diseases, and cancers. Molecular diagnostics dates back to 1980s but now has grown exponentially. The field has a wide range of applications including identifying individuals at risk of d...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2012
ISSN: 0009-9147,1530-8561
DOI: 10.1373/clinchem.2011.180802